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Image Search Results
Journal: NMR in biomedicine
Article Title: The impact of edema and fiber crossing on diffusion MRI metrics assessed in an ex vivo nerve phantom: multi-tensor model vs. diffusion orientation distribution function
doi: 10.1002/nbm.4414
Figure Lengend Snippet: In one metastatic lung cancer patient, extensive peritumoral edema occurred in the right hemisphere (A, b0 image), neighboring corpus callosum (CC) (A, DTI FA map). Three regions of interest (ROI, 3×4 voxels each) covering significant (rectangle 1), moderate (rectangle 2), and non-edematous (rectangle 3) CC are marked for analysis (A). DTI and DBSI diffusion ellipsoids (B) were generated using a lab-built Matlab code (MathWorks; Natick, MA, USA). The size of diffusion ellipsoids represents the signal fraction of individual tensors. Crossing-fibers resolved by DBSI are presented in different colors. DTI tensor ellipsoids suggest that crossing fibers and edema significantly decreases diffusion anisotropy (B). In contrast, DBSI derived anisotropic ellipsoids for single and crossing fibers display comparable diffusion anisotropy, eliminating the impact of edema.
Article Snippet: Diffusion-weighted data with 99 diffusion directions was analyzed with the
Techniques: Diffusion-based Assay, Generated, Derivative Assay